Esomeprazole 40 mg + Domperidone 30 mg Capsules

Esomeprazole 40 mg + Domperidone 30 mg Capsules
Esomeprazole 40 mg + Domperidone 30 mg Capsules
Price And Quantity
  • Box/Boxes
  • 100
  • Box/Boxes
  • 720 INR
    Product Specifications
    • Industrial,Commerical
    • General Drugs
    • Capsules
    • Adult
    • 40mg-30mg
    • Dry Place
      Product Description
      Indications and Usage:
      Acid peptic disease – both active disease treatment and for maintenance therapy.
      ● Gastroesophageal reflux disease and erosive esophagitis.
      ● Hypersecretory states like Z.E. syndrome etc.
      Mechanism of Actions:
      Domperidone is a peripheral dopamine D2-receptor antagonist, which regulates the motility of gastric and small intestinal smooth muscle. It increases the
      duration of antral and duodenal contractions and also LES resting pressure, thus stimulating gastric emptying and is also effective in relief of symptoms of reflux
      esophagitis. Antiemetic activity is due to the blockade of dopamine receptors in the chemoreceptor trigger zone. Esmoprazole inhibits the secretion of gastric
      acid by irreversibly blocking the enzyme system of H+/K+ ATPase of the gastric parietal cell. It is activated at an acidic pH to a sulphenamide derivative that
      binds irreversibly to H+/K+ ATPase, an enzyme system found at the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via
      exchange with K ions) into the gastric lumen.
      Drug Interactions:
      Esesmoprazole may have
      fewer drug interactions than esmoprazole. The absorption of certain drugs may be affected by stomach acidity. Therefore, esmoprazole and other PPIs that
      reduce stomach acid also reduce the absorption and concentration in blood of ketoconazole and increase the absorption and concentration in blood of digoxin
      This may lead to reduced effectiveness of ketoconazole or increased digoxin toxicity, respectively
      Pharmacology:
      Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone,
      located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and
      rhomboid fossa). Esmoprazole is a Proton pump inhibitors which block acid at the final common pathway of secretion-that is, at the proton pump-regardless of
      the stimulus of acid secretion, and thereby offer by far the most potent suppression of gastric acid.
      Trade Information
      • Mundra and Mumbai
      • Cash Advance (CA), Cash in Advance (CID)
      • 100 Per Day
      • 3-30 Hours
      • Yes
      • Sample costs shipping and taxes has to be paid by the buyer
      • Box, Carton
      • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
      • All India
      Contact Us

      405, Harvy Complex, Subhash Chowk, Near A-One School, Gurukul, Ahmedabad, Gujarat, 380052, India
      Phone :+918037301667